首页> 外国专利> METHODS OF COMBINING MESENCHYMAL STEM CELLS AND CARTILAGE CONTAINING ALLOGRAFTS, AND PRODUCTS OF COMBINED MESENCHYMAL STEM CELLS AND CARTILAGE CONTAINING ALLOGRAFTS

METHODS OF COMBINING MESENCHYMAL STEM CELLS AND CARTILAGE CONTAINING ALLOGRAFTS, AND PRODUCTS OF COMBINED MESENCHYMAL STEM CELLS AND CARTILAGE CONTAINING ALLOGRAFTS

机译:结合间充质干细胞和含软骨的同种异体移植物的方法,以及结合异体干细胞和含软骨的同种异体细胞的产品

摘要

There is disclosed a method of combining mesenchymal stem cells (MSCs) with an osteochondral allograft. In an embodiment, the method includes obtaining adipose tissue having MSCs with unwanted cells. The tissue is digested to form a cell suspension having MSCs and unwanted cells. The suspension is added to seed the allograft. The MSCs are allowed to attach to the allograft. There is disclosed an allograft product including MSCs with an osteochondral allograft. There is disclosed a method of combining MSCs with decellularized, morselized cartilage. In an embodiment, the method includes obtaining adipose tissue having MSCs with unwanted cells. The tissue is digested to form a cell suspension having MSCs and unwanted cells. The suspension is added to seed the cartilage. The MSCs are allowed to attach to the cartilage to. There is disclosed an allograft product including MSCs with morselized cartilage. Other embodiments are also disclosed.
机译:公开了一种将间充质干细胞(MSC)与同种异体软骨组合的方法。在一个实施方案中,该方法包括获得具有带有有害细胞的MSC的脂肪组织。消化组织以形成具有MSC和不需要的细胞的细胞悬浮液。加入悬浮液以接种同种异体移植物。允许MSC附着到同种异体移植物上。公开了包括具有骨软骨同种异体移植物的MSC的同种异体移植物产品。公开了一种将MSC与去细胞的,棋盘状软骨组合的方法。在一个实施方案中,该方法包括获得具有带有有害细胞的MSC的脂肪组织。消化组织以形成具有MSC和不需要的细胞的细胞悬浮液。加入悬浮液以播种软骨。允许MSC附着于软骨上。公开了包括具有软骨软骨的MSC的同种异体移植产品。还公开了其他实施例。

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