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NOVEL APOC-I ISOFORMS AND THEIR USE AS BIOMARKERS AND RISK FACTORS OF ATHEROSCLEROTIC DISEASE

机译：新型APOC-I亚型及其作为动脉粥样硬化疾病的生物标志物和风险因素的用途

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摘要

Novel isoforms of apolipoprotein C-I (apoC-I), namely apolipoprotein C-I₁(apoC-I₁) and apolipoprotein C-I₁′ (apoC-I₁′), both of which have a molecular weight of approximately 90 daltons greater than native apolipoprotein C-I (SEQ ID NO:6) and native apolipoprotein C-I′ (SEQ ID NO:7), are shown to be both biomarkers for diagnosing atherosclerotic disease as well as risk factors for subjects having increased risk of developing an atherosclerotic disease.

机译：载脂蛋白CI（apoC-I）的新型亚型，即载脂蛋白CI _{1 （apoC-I _{1 ）和载脂蛋白CI _{1 '（apoC-显示了I _{1 '），其分子量均比天然载脂蛋白CI（SEQ ID NO：6）和天然载脂蛋白CI'（SEQ ID NO：7）大约90道尔顿。既是诊断动脉粥样硬化疾病的生物标志物，又是患动脉粥样硬化疾病的风险增加的受试者的危险因素。}}}}

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公开/公告号US2014193846A1

专利类型
公开/公告日2014-07-10

原文格式PDF
申请/专利权人 RONALD D. MACFARLANE;CATHERINE J. MCNEAL;SUBROTO CHATTERJEE;
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申请/专利号US201114112670
发明设计人 CATHERINE J. MCNEAL;RONALD D. MACFARLANE;SUBROTO CHATTERJEE;
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申请日2011-12-23
分类号G01N33/92;
国家 US
入库时间 2022-08-21 16:05:23

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