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Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief
Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief
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机译:防止滥用的美沙酮可安全治疗药物滥用和缓解疼痛
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摘要
Provided is a drug substance and a method of treating an ailment comprising administering an oral dose of a drug product comprising the drug substance wherein the drug substance comprises an organic acid addition salt of methadone. The organic acid addition salt is selected from the group consisting of pamoate and xinafoate wherein the drug substance is bioavailable under gastrointestinal administration but is not bioavailable under administration at a mucosal membrane other than gastrointestinal or release from a depot injectable product.
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