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Method for producing polymer fine sphere and polymer fine sphere produced by the method

机译：制备聚合物细球的方法和通过该方法制备的聚合物细球

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摘要

The present invention relates to a method for preparing microspheres and microspheres prepared thereby, more particularly to a method for preparing a polymeric microsphere, including preparing an emulsion including a polymer compound, a drug, a water-insoluble organic solvent and a dispersion solvent and adding to the prepared emulsion a base or an acid to remove the water-insoluble organic solvent from the emulsion, a polymeric microsphere prepared thereby, and a composition for drug delivery including the microsphere. According to the present invention, a drug-containing polymer microsphere may be prepared quickly and simply without the solvent evaporation or solvent extraction process, thereby reducing water consumption and minimizing wastewater generation.

机译：制备微球的方法和由此制备的微球技术领域本发明涉及制备微球的方法和由此制备的微球，更具体地涉及制备聚合物微球的方法，包括制备包含高分子化合物，药物，水不溶性有机溶剂和分散溶剂的乳液，并加入向制备的乳液中加入碱或酸以从乳液中除去水不溶性有机溶剂，由此制得的聚合物微球和包括该微球的药物递送组合物。根据本发明，可以在没有溶剂蒸发或溶剂萃取过程的情况下快速且简单地制备含药物的聚合物微球，从而减少水的消耗并使废水的产生最小化。

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公开/公告号JP5588993B2

专利类型
公开/公告日2014-09-10

原文格式PDF
申请/专利权人イファユニバーシティ－インダストリーコラボレーションファウンデーション;エスケーケミカルスカンパニーリミテッド;
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申请/专利号JP20110536249
发明设计人サー;ホンキー;
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申请日2009-11-13
分类号A61K9/52;A61K47/32;A61K47/34;A61K47/14;A61K47/02;A61K47/04;A61K31/57;A61P5/34;A61K31/4196;A61P35;A61K31/5513;A61P25/18;A61K31/519;A61P43;A61K31/497;A61K31/5415;A61P29;A61K31/337;A61K31/27;A61K31/137;
国家 JP
入库时间 2022-08-21 16:12:10

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