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Device for the distribution of cardioprotective agents to the myocardium that are reperfusion of ischemic
Device for the distribution of cardioprotective agents to the myocardium that are reperfusion of ischemic
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机译:用于将心肌缺血再灌注的心脏保护剂分配到心肌的装置
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摘要
Implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion (106) of the medical device. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. Implantable medical devices may be coated or otherwise have affixed thereto agents for healing ischemic tissue. In one embodiment, a percutaneously delivered apparatus (100) which is positionable in a vessel in proximity to a treatment site is described. The apparatus comprises: a medical device; one or more agents, in therapeutic dosages, for treating ischemic tissue and; a delivery mechanism, comprising the one or more agents, operatively associated with the medical device and configured to deliver at least one agent to downstream ischemic tissue over a predetermined period of time.
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