首页> 外国专利> In vitro method of predicting/diagnosing risk of developing multifactorial diseases includes detecting presence/absence of genic marker of multifactorial disease and environmental marker in sample and comparing results with reference value

In vitro method of predicting/diagnosing risk of developing multifactorial diseases includes detecting presence/absence of genic marker of multifactorial disease and environmental marker in sample and comparing results with reference value

机译:预测/诊断多因素疾病风险的体外方法包括检测样品中是否存在多因素疾病基因标记和环境标记并将结果与​​参考值进行比较

摘要

In vitro method of predicting and/or diagnosing risk of developing multifactorial diseases in a subject, comprises (a) detecting presence or absence of at least one genetic marker of the multifactorial disease in a biological sample, (b) detecting presence or absence of at least one environmental marker in the biological sample, (c) optionally comparing detected level of the environmental marker with a reference value and (d) deducting the risk of developing multifactorial disease in the subject. An independent claim is included for identifying patients requiring monitoring of the occurrence of the multifactorial disease comprising in vitro diagnosing the patient having the risk of developing the disease, and optionally identifying the patient having the risk of developing the disease for establishing prophylaxis to reduce the risk of the multifactorial disease and/or monitoring the occurrence of the multifactorial disease.
机译:预测和/或诊断受试者发生多因素疾病的风险的体外方法包括(a)检测生物学样品中多因素疾病的至少一种遗传标记的存在或不存在,(b)检测至少一种遗传因子的存在或不存在。生物样品中的至少一种环境标志物,(c)任选地将检测到的环境标志物水平与参考值进行比较,以及(d)扣除受试者中发生多因素疾病的风险。包括一个独立权利要求,用于识别需要监视多因素疾病发生的患者,包括体外诊断具有发展为该疾病的风险的患者,以及可选地识别具有发展为该疾病的风险的患者,以建立预防措施以降低风险多因素疾病的发生和/或监测多因素疾病的发生。

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