首页> 外国专利> Use of 4-aminopiperidine derivatives as an agent to fight against wrinkles including wrinkles of expression and/or to relax skin and/or facial features, preferably skin of face and/or forehead

Use of 4-aminopiperidine derivatives as an agent to fight against wrinkles including wrinkles of expression and/or to relax skin and/or facial features, preferably skin of face and/or forehead

机译:4-氨基哌啶衍生物作为抗皱剂包括表达皱纹和/或松弛皮肤和/或面部特征,优选面部和/或前额皮肤的用途

摘要

Use of at least one 4-aminopiperidine derivative as an agent to fight against wrinkles including wrinkles of expression and/or to relax skin and/or facial features, is claimed. Use of at least one 4-aminopiperidine derivative of formula (I) and its salts, optical isomers or solvates, as an agent to fight against wrinkles including wrinkles of expression and/or to relax skin and/or facial features, is claimed. Alk1, Alk2 : divalent group comprising saturated linear 1-10C-alkylene, unsaturated linear 2-10C-alkylene, or optionally saturated branched 3-10C-alkylene; Ar1 : phenyl (optionally substituted with one or more substituents of R1, -OR1, -N(R1)(R2) or -COX) (preferred); X : OR1, NH(R1) or N(R1)(R2); R3 : divalent group comprising saturated linear 1-10C-alkylene, unsaturated linear 2-10C-alkylene or optionally saturated branched 3-10C-alkylene (all optionally substituted by one or more substituents of -OR1 or -N(R1)(R2), or H (preferred); R1, R2 : H, saturated linear 1-7C-alkyl, unsaturated linear 2-7C alkyl, or optionally saturated branched or cyclic 3-7C alkyl; and R4 : R1, -OR1 or -N(R1)(R2), preferably H. [Image].
机译:要求使用至少一种4-氨基哌啶衍生物作为抗皱剂,包括表情皱纹和/或松弛皮肤和/或面部特征。要求使用至少一种式(I)的4-氨基哌啶衍生物及其盐,旋光异构体或溶剂化物作为抗皱剂,包括表情皱纹和/或松弛皮肤和/或面部特征。 Alk1,Alk2:二价基团,其包含饱和的直链1-10C-亚烷基,不饱和的直链2-10C-亚烷基或任选地饱和的支链3-10C-亚烷基; Ar1:苯基(优选被R1,-OR1,-N(R1)(R2)或-COX的一个或多个取代基取代)(优选); X:OR1,NH(R1)或N(R1)(R2); R3:包含饱和线性1-10C-亚烷基,不饱和线性2-10C-亚烷基或任选地饱和的支链3-10C-亚烷基的二价基团(全部任选地被-OR1或-N(R1)(R2)的一个或多个取代基取代;或H(优选); R 1,R 2:H,饱和的直链1-7C-烷基,不饱和的直链2-7C烷基或任选地饱和的支链或环状3-7C烷基;和R 4:R 1,-OR1或-N( R1)(R2),最好是H。

著录项

  • 公开/公告号FR2983712A1

    专利类型

  • 公开/公告日2013-06-14

    原文格式PDF

  • 申请/专利权人 LOREAL;

    申请/专利号FR20110061528

  • 发明设计人 DALKO MARIA;

    申请日2011-12-13

  • 分类号A61K8/49;A61K8/72;A61K8/92;A61Q19/08;

  • 国家 FR

  • 入库时间 2022-08-21 16:21:00

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