首页> 外国专利> USING MONOCLONAL ANTIBODIES FOR IDENTIFYING YAMAGATA OR VICTORIAN INFLUENZA B VIRAL EVOLUTION LINE, HYBRIDOMA 4H7 STRAIN FOR PREPARING MONOCLONAL ANTIBODIES USED TO IDENTIFY INFLUENZA B VIRUSES IN YAMAGATA BRANCH, HYBRIDOMA B/4H1 STRAIN FOR PREPARING MONOCLONAL ANTIBODIES USED TO IDENTIFY INFLUENZA B VIRUSES IN VICTORIAN BRANCH

USING MONOCLONAL ANTIBODIES FOR IDENTIFYING YAMAGATA OR VICTORIAN INFLUENZA B VIRAL EVOLUTION LINE, HYBRIDOMA 4H7 STRAIN FOR PREPARING MONOCLONAL ANTIBODIES USED TO IDENTIFY INFLUENZA B VIRUSES IN YAMAGATA BRANCH, HYBRIDOMA B/4H1 STRAIN FOR PREPARING MONOCLONAL ANTIBODIES USED TO IDENTIFY INFLUENZA B VIRUSES IN VICTORIAN BRANCH

机译:使用单克隆抗体鉴定山形或维多利亚型流感病毒HYBRIDOMA 4H7株的进化谱,以鉴定用于分离美洲棉兰分枝杆菌中的矢状斑马病毒的细菌,以鉴定Y / B病毒的细菌。

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention discloses using the monoclonal antibodies (MCAs) produced by the hybridomas B/4H1 and 4H7 and directed to variable determinants as a part of influenza B virus proteins. The hybridoma B/4H1 and 4H7 strains are deposited in the Russian Collection of Vertebral Cell Cultures (RKKK P) under Nos. 719 D and 720 D, respectively. The two current influenza B viral evolution lines are identified with using the MCAs B/4H1 and MCAs 4H7 directed to variable determinants of Victorian-type and Yamagata-type influenza B hemagglutinin, respectively.;EFFECT: using the prepared MCA kit enables identifying the newly recovered influenza B viruses Besides, the MCAs under the invention may be used to study the antigenic structure and variability of this agent, to identify them as belonging to a specific evolution line; the MCAs may be also used to construct the diagnostic test systems.;3 cl, 12 dwg, 8 ex
机译:领域:本发明公开了使用由杂交瘤B / 4H1和4H7产生并针对可变决定簇作为B型流感病毒蛋白一部分的单克隆抗体(MCA)。杂交瘤B / 4H1和4H7菌株分别以719 D和720 D号保藏在俄罗斯椎细胞培养物保藏中心(RKKK P)。使用MCA B / 4H1和MCA 4H7分别鉴定出维多利亚型和山形B型流感血凝素的可变决定簇来鉴定两种当前的B型流感病毒进化谱系;效果:使用准备好的MCA试剂盒可以识别新的回收的乙型流感病毒此外,根据本发明的MCA可用于研究该试剂的抗原结构和变异性,以鉴定它们属于特定的进化系; MCA也可用于构建诊断测试系统。; 3 cl,12 dwg,8 ex

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