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首页> 外国专利> METHOD FOR PREPARING WEAKLY POSITIVE REFERENCE SERUM CONTAINING AD AND AY SUBTYPES OF HBsAg

METHOD FOR PREPARING WEAKLY POSITIVE REFERENCE SERUM CONTAINING AD AND AY SUBTYPES OF HBsAg

机译：HBsAg AD和AY亚型弱阳性参考血清的制备方法

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FIELD: medicine.;SUBSTANCE: invention represents a method for preparing weakly positive reference serum containing AD and AY subtypes of HBsAg involving donor serum sampling with ELISA, titration of the positive serum containing AD & AY subtypes of HBsAg in a dissolving stabilised solution, genotyping, thermal degradation test for establishing panel shelf life, differing by the fact that the positive reference serums containing AY and AD subtypes of HBsAg are dissolved to the range of the concentrations of 0.05 to 0.025 IU/ml and viscosity equal to that of normal human serum; and the dissolving stabilised solution is presented by negative defibrinated and lipid-free serum containing no markers of HBV infection which is to be detected by the test system of interest.;EFFECT: invention provides detection of HBV infection at the earlier stage of the disease and enables creating and controlling the test system quality.;5 cl, 2 tbl, 1 ex
机译：发明领域本发明涉及一种用于制备含有HBsAg的AD和AY亚型的弱阳性参考血清的方法，该方法涉及用ELISA对供体血清进行采样，在溶解稳定的溶液中滴定含有HBsAg的AD和AY亚型的阳性血清，进行基因分型。 ，用于建立面板保质期的热降解试验，不同之处在于，含有AY和AD亚型的HBsAg的阳性参照血清溶解至浓度范围为0.05至0.025 IU / ml，粘度与正常人血清相同;溶解的稳定溶液由阴性的无纤维化且无脂质的血清提供，该血清不含要检测的HBV感染的标志物;效果：本发明提供了在疾病早期阶段检测HBV感染的方法，并且能够创建和控制测试系统质量。; 5 cl，2 tbl，1 ex

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