首页> 外国专利> PREPARATION FOR REPAIRING CARTILAGE TISSUE, ESPECIALLY ARTICULAR CARTILAGE DEFECTS

PREPARATION FOR REPAIRING CARTILAGE TISSUE, ESPECIALLY ARTICULAR CARTILAGE DEFECTS

机译:修复软骨组织,特别是关节软骨缺损的准备

摘要

The invention relates to preparations which are suitable for repairing enchondral or osteochondral defects (4) by means of implantation, said preparations comprising a cartilage element (A) and optionally a bone element (B) which is connected to the cartilage element (A). The cartilage element (A) can already contain cells during the implantation or is populated after the implantation with cells migrating from surrounding tissue. The aim of the invention is to better equip the cartilage element (A) of one such preparation for integration into the surrounding tissue and/or for an easy-to-achieve, primary stability. To this end, said cartilage element is not homogeneously embodied but has different characteristics in a peripheral and/or basal region (2, 3) to those in a central region (3). Said differing characteristics (A) relate to the structure and/or composition of the matrix used and/or to the cells established in the matrix, and are in no way used to prevent the migration of cells into the preparation from the surrounding tissue.
机译:本发明涉及适于通过植入来修复软骨或骨软骨缺损(4)的制剂,所述制剂包括软骨元件(A)和任选地连接至软骨元件(A)的骨元件(B)。软骨元件(A)在植入过程中可能已经包含细胞,或在植入后填充有从周围组织迁移的细胞。本发明的目的是更好地装备一种这样的制剂的软骨元件(A)以整合到周围组织中和/或易于实现的基本稳定性。为此,所述软骨元件不是均匀地构成,而是在外围和/或基底区域(2、3)中具有与在中央区域(3)中不同的特征。所述不同的特征(A)涉及所使用的基质的结构和/或组成和/或涉及在基质中建立的细胞,并且决不用于防止细胞从周围组织迁移到制剂中。

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