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.DELTA.12 DESATURASES SUITABLE FOR ALTERING LEVELS OF POLYUNSATURATED FATTY ACIDS IN OLEAGINOUS YEAST
.DELTA.12 DESATURASES SUITABLE FOR ALTERING LEVELS OF POLYUNSATURATED FATTY ACIDS IN OLEAGINOUS YEAST
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机译:Δ12脱饱和酶可用于改变油脂酵母中多不饱和脂肪酸的水平
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摘要
The present invention relates to fungal .DELTA.12 fatty acid desaturases thatare able to catalyze the conversion of oleic acid to linoleic acid (LA; 18:2).Nucleic acid sequences encoding the desaturases, nucleic acid sequences whichhybridize thereto, DNA constructs comprising the desaturase genes, andrecombinant host microorganisms expressing increased levels of the desaturasesare described. Methods of increasing production of specific .omega.-3 and.omega.-6 fatty acids by over-expression of the .DELTA.12 fatty aciddesaturases are also described herein.
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