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CLASS III SLRP AGONISTS FOR THE REDUCTION OF BLOOD VESSEL FORMATION

机译：III类SLRP激动剂，可减少血管形成

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摘要

The invention relates to the use of an agent that promotes class III SLRP activity in the manufacture of a medicament for the inhibition of blood vessel formation. In addition the invention relates to the use of an agent that promotes class III SLRP activity in the manufacture of a medicament for the prevention and/or treatment of conditions characterized by excessive activity and/or migration of monocytes and/or macrophages. Suitable agents may include class III SLRPs such as opticin. Methods of treatment using agents able to promote class III SLRP activity are also provided.

机译：本发明涉及促进III类SLRP活性的试剂在制备用于抑制血管形成的药物中的用途。另外，本发明涉及促进III类SLRP活性的试剂在制备用于预防和/或治疗以单核细胞和/或巨噬细胞的过度活性和/或迁移为特征的病症的药物中的用途。合适的试剂可以包括III类SLRP，例如视黄质。还提供了使用能够促进III类SLRP活性的试剂的治疗方法。

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公开/公告号PT1638591E

专利类型
公开/公告日2013-05-22

原文格式PDF
申请/专利权人 THE UNIVERSITY OF MANCHESTER;
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申请/专利号PT20040735259T
发明设计人 PAUL N. BISHOP;
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申请日2004-05-28
分类号A61K38/16;A61K31;A61K38/17;A61P19/02;A61P27;A61P27/02;A61P35;A61P43;
国家 PT
入库时间 2022-08-21 16:40:08

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