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Dual targeting of miR-208a or miR-208b and miR-499 in the treatment of cardiac disorders or musculoskeletal disorders

机译:将miR-208a或miR-208b和miR-499双重靶向治疗心脏病或肌肉骨骼疾病

摘要

594365 Provided is the use of an inhibitor of miR-208a or miR-208b and an inhibitor of miR-499 in the manufacture of a medicament for reducing a cardiac stress response in a subject in need thereof, wherein said medicament is formulated for administration to said subject and wherein the cardiac stress response is reduced in the subject within two weeks of administration of the inhibitors.
机译:594365提供了miR-208a或miR-208b的抑制剂和miR-499的抑制剂在制备用于减少有此需要的受试者的心脏应激反应的药物中的用途,其中所述药物被配制用于给药至所述受试者,并且其中在施用抑制剂的两周内该受试者的心脏应激反应降低。

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