首页> 外国专利> ADVANCE PROCESS FOR AVASCULAR NECROSIS TREATMENT USING AUTOLOGUS BONE MARROW MESENCHYMAL STEM CELLS (BM MSCS) AND PLATELET RICH PLASMA (PRP) COMBINATION

ADVANCE PROCESS FOR AVASCULAR NECROSIS TREATMENT USING AUTOLOGUS BONE MARROW MESENCHYMAL STEM CELLS (BM MSCS) AND PLATELET RICH PLASMA (PRP) COMBINATION

机译:自体标志骨髓间充质干细胞(BM MSCS)和富血小板血浆(PRP)联合治疗血管坏死的进展

摘要

The present invention Advance process for Avascular Necrosis Treatment using Autologous Bone Marrow Mesenchymal Stem Cells (BM MSCs) and Platelet Rich Plasma (PRP) combination makes use of optimal delivery of growth factors and Mesenchymal Stem Cells (MSCs) to treat avascular necrosis. Activated PRP consists of several growth factors and this also works as a biological scaffold. This scaffold in combination with growth factors facilitates neovascularization of AVN bone. In addition, this scaffold helps transplanted MSC to engraft and differentiate in to osteocytes or chondrocytes at the injury site. . This minimally invasive procedure allows the delivery of Platelet Rich Plasma (PRP) and Bone Marrow Mesenchymal Stem Cells (BM MSCs) through a fine needle.
机译:使用自体骨髓间充质干细胞(BM MSC)和富血小板血浆(PRP)组合的本发明用于无血管坏死治疗的先进方法利用生长因子和间充质干细胞(MSC)的最佳递送来治疗血管坏死。活化的PRP由几种生长因子组成,也可以作为生物支架。该支架与生长因子结合促进AVN骨的新血管形成。另外,该支架有助于移植的MSC在损伤部位移植并分化为骨细胞或软骨细胞。 。这种微创程序允许通过细针递送富含血小板的血浆(PRP)和骨髓间充质干细胞(BM MSC)。

著录项

  • 公开/公告号IN2012MU03727A

    专利类型

  • 公开/公告日2013-03-08

    原文格式PDF

  • 申请/专利权人

    申请/专利号IN3727/MUM/2012

  • 申请日2012-12-31

  • 分类号C12N5/00;

  • 国家 IN

  • 入库时间 2022-08-21 16:41:03

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