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Sigma ligands for the potentiation of Analgesic effect of opioids and opioids in Postoperative PAIN and the Attenuation of the unit for the same

机译:用于增强术后PAIN中阿片类药物和阿片类药物镇痛作用的Sigma配体及其单位的衰减

摘要

The Invention relates to a combination comprising a Sigma ligand of formula (1) and an opioid or opioid for use in the Prevention and / or treatment of Pain developed as a result of surgery, especially Peripheral neuropathic pain, allodynia, causalgia, hiperalgesi Hyperpathia, hyperaesthesia, neuritis, neuralgia, or Neuropathy.The Invention also relates to the Sigma ligands of formula (1) for use in the potentiation of the Analgesic effect of an opioid or opioid and / or decreasing dependence induced by the same, when using this opioid or opioid in the Prevention and / or treatment of the OJ Lor developed as a result of Surgery.
机译:本发明涉及包含式(1)的Sigma配体和阿片样物质或阿片样物质的组合,其用于预防和/或治疗由于外科手术而引起的疼痛,特别是周围神经性疼痛,异常性疼痛,因痛,海马氏痛症本发明还涉及式(1)的Sigma配体,其用于增强阿片样物质或阿片样物质的镇痛作用和/或在使用时降低由其诱导的依赖性。这种阿片样物质或阿片样物质在预防和/或治疗OJ Lor中是由于外科手术而开发的。

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