首页> 外国专利> The production method of vaccine adsorbent (emulsifiable/water latex, polyurethane 80 and sorbite trinitroformate) includes (i) forming the first emulsifier from one container to another in the same container, forming the second emulsifier, (i) the first emulsifier of microfluids, forming the second emulsifier. Xiyong

The production method of vaccine adsorbent (emulsifiable/water latex, polyurethane 80 and sorbite trinitroformate) includes (i) forming the first emulsifier from one container to another in the same container, forming the second emulsifier, (i) the first emulsifier of microfluids, forming the second emulsifier. Xiyong

机译：疫苗吸附剂（乳化剂/水乳胶，聚氨酯80和三硝酸山梨酯）的生产方法包括（i）在同一个容器中从一个容器到另一个容器形成第一乳化剂，形成第二乳化剂，（i）微流体的第一乳化剂，形成第二种乳化剂。希勇

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U. Application No. S. P 201399 describes M amp; eacute; all adjvante; oacute; n used for latex and amp; amp; vaccine, since adyvante includes escualeno, polisorbato 80 and sorbit amp; trinitronitric acid; Aacute; N, because M amp; eacute; n; is used for latex and amperometric vaccine; All of these steps include: (1) forming the first latex and ampere; oacute; N, the first size and amp; ntilde; or averaging oil drops using a homogenizer.wherein the first emulsion is formed by circulation comprising: (a) a type I circulation that transfers the components of the first emulsion between a first container and a homogenizer, followed by: (b) a type II circulation that transfers the components of the first emulsion between the first container to a second container, through the same homogenizer, where all the components of the emulsion from the first container are made pass through the homogenizer to the second container, and then,all the components of the emulsion from the second container are passed through the homogenizer back to the first container; (ii) microfluidize the first emulsion to form a second emulsion, circulating the components of the second emulsion through a microfluidization equipment several times, where the circulation comprises transferring the components of the the second emulsion from a first emulsion container through the microfluidization equipment to a second emulsion container,Then trav amp; eacute; s; the same microfluidic device; oacute; n P

机译：U.申请号S。 P GT; 201399描述了M amp;敏锐所有的ac n用于乳胶和放大器; amp;疫苗，因为Adyvante包括escualeno，polisorbato 80和sorbit amp;三硝基硝酸急性N，因为M放大器;敏锐n;用于乳胶和安培疫苗;所有这些步骤包括：（1）形成第一乳胶和安培; ac N，第一大小和放大器;小提琴其中第一乳液是通过循环形成的，该循环包括：（a）I型循环，该循环在第一容器和均质器之间转移第一乳液的成分，然后：（b）II型通过相同的均质器将第一乳液的成分在第一容器之间转移至第二容器的循环，其中使来自第一容器的乳液的所有成分均通过均质器到达第二容器，然后将所有来自第二容器的乳液组分通过均质器回到第一容器; （ii）将第一乳液微流化以形成第二乳液，使第二乳液的成分通过微流化设备循环数次，其中循环包括将第二乳液的成分从第一乳液容器通过微流化设备转移至第二乳液。第二个乳液容器，然后TRAV AMP;敏锐s;相同的微流体装置; ac n P GT;

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公开/公告号CL2012001399A1

专利类型
公开/公告日2013-03-08

原文格式PDF
申请/专利权人 NOVARTIS AG.;
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申请/专利号CL20120001399
发明设计人 RUECKL HARALD;SCHEFFCZIK HANNO;SANTRY BARBARA.;
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申请日2012-05-30
分类号A61K9/107;A61K39/39;
国家 CL
入库时间 2022-08-21 16:42:08

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