首页> 外国专利> compound, pharmaceutical composition, method for inhibiting cell growth, method for treating an inflammatory disease and method for treating an autoimmune disease, destructive bone damage, proliferative disorders, infectious diseases, viral diseases, fibrotic diseases or neurodegenerative diseases

compound, pharmaceutical composition, method for inhibiting cell growth, method for treating an inflammatory disease and method for treating an autoimmune disease, destructive bone damage, proliferative disorders, infectious diseases, viral diseases, fibrotic diseases or neurodegenerative diseases

机译：化合物，药物组合物，抑制细胞生长的方法，炎性疾病的治疗方法和自身免疫性疾病，破坏性骨损伤，增生性疾病，感染性疾病，病毒性疾病，纤维化疾病或神经退行性疾病的治疗方法

页面导航

摘要
著录项
相似文献

摘要

COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD TO INHIBIT CELLULAR GROWTH, METHOD FOR TREATING AN INFLAMMATORY DISEASE, METHOD FOR TREATING A DESTRUCTIVE BONE DISEASES, NEUTRAL DISEASES The invention relates to azabenzothiophenyl compounds of Formula I with anticancer activity and / or antiinflammatory activity and more specifically to azabenzothiophenyl compounds which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ and in vivo diagnosis or for the treatment of mammalian cells or associated pathological conditions.

机译：化合物，药物组合物，抑制细胞生长的方法，治疗发炎性疾病的方法，治疗破坏性骨疾病，中性疾病的方法本发明涉及具有抗癌活性和/或抗炎活性的式I的氮杂苯并硫代苯基化合物，更具体地涉及氮杂苯并硫代苯基抑制MEK激酶活性的化合物。本发明提供了用于抑制哺乳动物中异常细胞生长或治疗过度增殖性疾病或治疗炎性疾病的组合物和方法。本发明还涉及使用所述化合物进行体外，原位和体内诊断或治疗哺乳动物细胞或相关病理状况的方法。

著录项

公开/公告号BRPI0714629A2

专利类型
公开/公告日2013-05-07

原文格式PDF
申请/专利权人 GENENTECH INC.;
展开▼

申请/专利号BR2007PI14629
发明设计人 STEPHEN PRICE;KAREN WILLIAMS;PASCAL PIERRE SAVY;HAZEL JOAN DYKE;JOHN GARY MONTANA;MARK S. STANLEY;LIANG BAO;
展开▼

申请日2007-08-20
分类号C07D495/04;A61K31/4743;A61P29;A61P35;
国家 BR
入库时间 2022-08-21 16:42:19

相似文献

专利
外文文献