首页> 外国专利> monoclonal antibody specific for an inactivated feline immunodeficiency virus (fiv) encoded glycoprotein epitope, cell lines and methods for determining the potency and amount of fiv, as well as for detecting a fiv encoded glycoprotein epitope.

monoclonal antibody specific for an inactivated feline immunodeficiency virus (fiv) encoded glycoprotein epitope, cell lines and methods for determining the potency and amount of fiv, as well as for detecting a fiv encoded glycoprotein epitope.

机译：对灭活的猫免疫缺陷病毒（fiv）编码的糖蛋白表位具有特异性的单克隆抗体，细胞系和确定fiv的效力和数量以及检测fiv编码的糖蛋白表位的方法。

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摘要

Monoclonal antibody (I) specific for an epitope unique to an inactivated feline immunodeficiency virus (FIV)-encoded glycoprotein, is new. Independent claims are also included for the following: (1) preparation of (I); and (2) a hybridoma cell line suitable for obtaining monoclonal antibodies specific for an epitope unique to an inactivated FIV-encoded glycoprotein prepared by immunizing a suitable host with a partially purified, inactivated FIV, screening the host for high FIV-specific antibody response, and fusing splenocytes from the host with a suitable myeloma cell line, and screening hybridomas for specific reactivity with inactivated FIV.

机译：对灭活的猫免疫缺陷病毒（FIV）编码的糖蛋白特有的表位具有特异性的单克隆抗体（I）是新的。还包括以下方面的独立权利要求：（1）（I）的制备; （2）杂交瘤细胞系，该杂交瘤细胞系适合于获得对灭活的FIV编码糖蛋白特异的表位具有特异性的单克隆抗体，该单克隆抗体是通过用部分纯化的灭活的FIV免疫合适的宿主，筛选宿主的高FIV特异性抗体应答而制备的，将宿主的脾细胞与合适的骨髓瘤细胞系融合，并筛选杂交瘤与灭活的FIV的特异性反应性。

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公开/公告号BR0303500B1

专利类型
公开/公告日2013-09-17

原文格式PDF
申请/专利权人
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申请/专利号BR20030303500
发明设计人 CHENGJIN MICHAEL HUANG;
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申请日2003-09-10
分类号C07K16/10;G01N33/53;C07K16;C12N5/10;C12N5/12;C12N15/02;C12P21/08;G01N33/531;G01N33/541;G01N33/569;G01N33/577;
国家 BR
入库时间 2022-08-21 16:42:28

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