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Method of making microneedle array and device for applying microneedle array to skin

机译:制造微针阵列的方法和将微针阵列应用于皮肤的装置

摘要

Microneedle arrays and drug delivery devices are provided for transdermally delivering a drug formulation to a patient. The microneedle array device includes a substantially planar substrate having an array of apertures; and a plurality of microneedles projecting at angle from the planar substrate, the microneedles having a base portion integrally connected to the substrate, a tip end portion distal to the base portion, and body portion therebetween, wherein each microneedle has at least one channel extending substantially from the base portion through at least a part of the body portion, the channel being open along at least part of the body portion and in fluid communication with at least one of the apertures in the substrate. In a preferred embodiment, each microneedle has a substantially rectangular cross-sectional shape and the channel is open to two opposing surfaces of the microneedle.
机译:提供了微针阵列和药物递送装置,用于将药物制剂透皮递送至患者。所述微针阵列装置包括具有孔阵列的基本平面的基板;所述孔具有阵列。多个微针从平面基板以一定角度突出,该微针具有与基板一体地连接的基部,远离基部的顶端部,以及它们之间的主体部,其中,各微针具有至少一个大致延伸的通道。通道从基部穿过主体部分的至少一部分,通道沿主体部分的至少一部分开口,并与基板中的至少一个孔流体连通。在一个优选的实施方案中,每个微针具有基本矩形的横截面形状,并且所述通道向微针的两个相对表面敞开。

著录项

  • 公开/公告号US8414548B2

    专利类型

  • 公开/公告日2013-04-09

    原文格式PDF

  • 申请/专利权人 VADIM V. YUZHAKOV;

    申请/专利号US20100694314

  • 发明设计人 VADIM V. YUZHAKOV;

    申请日2010-01-27

  • 分类号A61M5/32;B22D17/00;

  • 国家 US

  • 入库时间 2022-08-21 16:43:15

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