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DETERMINING CODON DISTRIBUTION AND/OR BASE PAIR DISTANCE BETWEEN CODONS IN A NUCLEIC ACID

机译：确定核酸中密码子之间的密码子分布和/或碱基对距离

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摘要

The present invention relates to methods for the design and/or production of a probe or primer that is capable of hybridizing to a plurality of sites in a sample comprising nucleic acid. Furthermore, the present invention provides methods for detecting and amplifying nucleic acid using such a probe or primer, for example, for identification of a strain, species or genera. Probe or primer sequences are determined by reference to codon usage bias of a target nucleic acid. In addition, the present invention provides methods for determining codon distribution and/or base pair distance between codons in a nucleic acid.

机译：本发明涉及设计和/或生产能够与包含核酸的样品中的多个位点杂交的探针或引物的方法。此外，本发明提供了使用这种探针或引物检测和扩增核酸的方法，例如，用于鉴定菌株，物种或属。通过参考靶核酸的密码子使用偏好来确定探针或引物序列。另外，本发明提供了确定核酸中密码子之间的密码子分布和/或碱基对距离的方法。

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公开/公告号US2012295251A1

专利类型
公开/公告日2012-11-22

原文格式PDF
申请/专利权人 MURALI NAYUDU;ANDREW FRANKLIN;YAFEI ZHANG;MARK JOHN GIBBS;TERRY JOHN MURPHY;ADRIAN JOHN GIBBS;SHEBA KHAN;CHRISTIAN SAMUNDSETT;
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申请/专利号US201013514524
发明设计人 ANDREW FRANKLIN;CHRISTIAN SAMUNDSETT;TERRY JOHN MURPHY;SHEBA KHAN;YAFEI ZHANG;MURALI NAYUDU;MARK JOHN GIBBS;ADRIAN JOHN GIBBS;
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申请日2010-12-09
分类号C12Q1/68;C07H21/04;C12Q1/70;
国家 US
入库时间 2022-08-21 16:48:44

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