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Three-dimensional culture extracellular matrix structure formation models, methods and evaluation method of skin structure formation to evaluate the extracellular matrix structure formation ability to promote the drug using it
Three-dimensional culture extracellular matrix structure formation models, methods and evaluation method of skin structure formation to evaluate the extracellular matrix structure formation ability to promote the drug using it
PPROBLEM TO BE SOLVED: To provide a model for evaluating extracellular matrix structure formation, a method for evaluating ability to promote extracellular matrix structure formation using medicine's ability to promote collagen fiber structure formation as an index using the evaluation model, and a method for evaluating skin structure formation, especially dermis structure formation. PSOLUTION: There is provided a model for forming three-dimensionally cultured extracellular matrix structure having the feature that extracellular matrix-producing cells are cultured on a culture supporter or carrier in which the generation of second harmonic generation (SHG) light is not detected even when an ultrashort light pulse is radiated as incident light. PCOPYRIGHT: (C)2010,JPO&INPIT
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