首页> 外国专利> Cutpoints in PTEN protein expression that accurately identify tumors and predict drug response to PAN-ErbB inhibitors

Cutpoints in PTEN protein expression that accurately identify tumors and predict drug response to PAN-ErbB inhibitors

机译:PTEN蛋白表达的切入点可准确识别肿瘤并预测对PAN-ErbB抑制剂的药物反应

摘要

A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value.
机译:PTEN蛋白表达定量测量中的一个切入点,可准确识别具有两个PTEN基因失活等位基因的肿瘤。 PTEN评分标准化为PTEN无效的患者将接受pan-ErbB酪氨酸激酶抑制剂治疗。通过将肿瘤PTEN OD表达值与非恶性PTEN OD表达值进行比较,获得标准化的PTEN蛋白表达评分。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号