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Amino acid composition for preventing or treating senile anemia

机译:预防或治疗老年性贫血的氨基酸组合物

摘要

Anemia often occurs with aging. Thus, the first object is to develop an effective therapeutic agent for prevention of senile anemia. An elderly population is growing toward the future. Thus, the second object is to provide an inexpensive, effective anti-aging agent which produces little adverse side effect. It is found for the first time that a preparation comprising, as an active ingredient, an amino acid composition comprising at least isoleucine (Ile), tryptophan (Trp), threonine (Thr), valine (Val), histidine (His), phenylalanine (Phe), methionine (Met), lysine (Lys) and leucine (Leu) is capable of ameliorating and recovering senile anemia, and a senile anemia-treating agent, a senile anemia-preventive agent, a cell senescence-preventive agent, a muscle anabolism-promoting agent and a muscle catabolism-preventive agent can be provided. An example of the amino acid composition comprises aspartic acid (Asp), alanine (Ala), arginine (Arg), isoleucine (Ile), glycine (Gly), glutamic acid (Glu), serine (Ser), tyrosine (Tyr), tryptophan (Trp), threonine (Thr), valine (Val), histidine (His), phenylalanine (Phe), proline (Pro), methionine (Met), lysine (Lys) and leucine (Leu).
机译:贫血常伴随衰老而发生。因此,第一个目的是开发一种预防老年性贫血的有效治疗剂。老年人口正朝着未来增长。因此,第二个目的是提供一种廉价,有效的抗衰老剂,其几乎不产生不利的副作用。首次发现包含氨基酸组合物作为活性成分的制剂,所述氨基酸组合物至少包含异亮氨酸(Ile),色氨酸(Trp),苏氨酸(Thr),缬氨酸(Val),组氨酸(His),苯丙氨酸(Phe),蛋氨酸(Met),赖氨酸(Lys)和亮氨酸(Leu)能够改善和恢复老年性贫血,以及老年性贫血治疗剂,老年性贫血预防剂,细胞抗衰老剂,可以提供肌肉合成代谢促进剂和肌肉分解代谢预防剂。氨基酸组合物的实例包括天冬氨酸(Asp),丙氨酸(Ala),精氨酸(Arg),异亮氨酸(Ile),甘氨酸(Gly),谷氨酸(Glu),丝氨酸(Ser),酪氨酸(Tyr),色氨酸(Trp),苏氨酸(Thr),缬氨酸(Val),组氨酸(His),苯丙氨酸(Phe),脯氨酸(Pro),蛋氨酸(Met),赖氨酸(Lys)和亮氨酸(Leu)。

著录项

  • 公开/公告号JP5220415B2

    专利类型

  • 公开/公告日2013-06-26

    原文格式PDF

  • 申请/专利权人 株式会社明治;

    申请/专利号JP20070534444

  • 发明设计人 浅見 幸夫;

    申请日2006-09-06

  • 分类号A61K31/198;A61K31/401;A61K31/405;A61K31/4172;A61P7/06;

  • 国家 JP

  • 入库时间 2022-08-21 16:57:54

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