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Methods for treating alcohol addiction, alcohol use disorders and alcohol abuse, including administration of dihydromyricetin
Methods for treating alcohol addiction, alcohol use disorders and alcohol abuse, including administration of dihydromyricetin
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机译:治疗酒精成瘾,酒精使用障碍和酒精滥用的方法,包括给予双氢杨梅素
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摘要
Disclosed herein are methods for treating alcohol intoxication, alcohol use disorders and alcohol abuse which comprise the administration of dihydromyricetin. As disclosed herein, dihydromyricetin potentiates the activity of GABAARs having the alpha4-beta-delta subunit which is associated with the effects of ethanol, antagonizes the actions of ethanol on the GABAARs, acts on the benzodiazepine sites of GABAARs, and inhibits, reduces and/or reverses some or all of the GABAAR plasticity which is caused by exposure to ethanol.
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