首页> 外国专利> EXPRESSION VECTOR FOR BIOTRANSFORMATION OF MARCHANTIALES, BIOTRANSFORMATION PRODUCT OF MARCHANTIALES, AND METHOD FOR PRODUCING PROSTAGLANDIN BY THE BIOTRANSFORMATION PRODUCT

EXPRESSION VECTOR FOR BIOTRANSFORMATION OF MARCHANTIALES, BIOTRANSFORMATION PRODUCT OF MARCHANTIALES, AND METHOD FOR PRODUCING PROSTAGLANDIN BY THE BIOTRANSFORMATION PRODUCT

机译：菌体生物转化的表达载体，菌体生物转化产物以及用该生物转化产物生产前列腺素的方法

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摘要

PROBLEM TO BE SOLVED: To provide an expression vector for biotransformation of a Marchantiales for making a high-expression of a cyclooxygenase involved in the biosynthesis of prostaglandins in the Marchantiales; to provide a biotransformation product of Marchantiales obtained by introducing the vector in the Marchantiales; and to provide a method for producing in vitro of a prostaglandin using extract of the biotransformation product of Marchantiales.SOLUTION: An expression vector for biotransformation of a Marchantiales includes: (A) DNA encoding a protein derived from an organism of Gracilariales having cyclooxygenase activity; and (B) DNA, situated upstream thereof, having 5'-UTR activity in Marchantiales biological cells.

机译：要解决的问题：提供一种用于马氏藻的生物转化的表达载体，以使参与马氏藻中前列腺素生物合成的环氧合酶高表达。提供通过将载体引入马奇蒂纳莱斯而获得的马奇蒂纳莱斯的生物转化产物;解决方案：用于进行Marchantiales生物转化的表达载体包括：（A）编码来源于具有环加氧酶活性的Gracilariales生物体的蛋白质的DNA;以及（B）在马氏anti属生物细胞中位于其上游的具有5'-UTR活性的DNA。

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公开/公告号JP2013183639A

专利类型
公开/公告日2013-09-19

原文格式PDF
申请/专利权人 ISHIKAWA PREFECTURAL PUBLIC UNIV CORP;
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申请/专利号JP20120048490
发明设计人 OYAMA KANJI;KOBAYASHI MIHO;KANEMOTO KOSUKE;TOKUMOTO SHUICHI;OKIMURA YUKIO;TANAKA KOJIRO;YOSHIDA MASAAKI;
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申请日2012-03-05
分类号C12N15/09;C12N5/10;A01H11;C12P7/38;A61K31/5575;A61P43;C07C57/03;C07C51/47;
国家 JP
入库时间 2022-08-21 17:03:14

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