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METHOD OF ELECTROCHEMICAL LYSIS AND PHOTODYNAMIC THERAPY OF CHOROIDAL MELANOMA
METHOD OF ELECTROCHEMICAL LYSIS AND PHOTODYNAMIC THERAPY OF CHOROIDAL MELANOMA
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机译：脉络膜黑色素的电化学裂解和光动力治疗方法
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摘要
FIELD: medicine.;SUBSTANCE: invention relates to medicine, and can be used in ophthalmology for electrochemical lysis and photodynamic therapy of choroidal melanomas (CM) of central and pre-equatorial localisation with prominence more than 4 mm. 2 hours after photosensibiliser PS introduction on tumour zone on sclera applied and sewn to it is electrode-anode, made in form of net from platinum wire with hole in the centre and corresponding in shape to shape of tumour base projection on sclera, in size being 1 mm smaller than tumour base on entire perimetre; laser light conductor with diffuser, made on entire length of intratumour part of light conductor, is introduced into tumour intravitreally, at distance of 4.0 mm from distal end of light conductor located is platinum insert-cathode; after that, electrochemical lysis of tumour with simultaneous ablation of tumour destruction products is performed, after which by means of laser light conductor intrastromal irradiation of tumour with laser radiation with wavelength, corresponding to maximum of PS absorption of light irradiation, is performed, tumour is ablated.;EFFECT: invention ensures reduction of trauma by electrochemical laser and photodynamic therapy of choroidal melanoma, preservation of sclera intactness in zone of tumour base, complete destruction and ablation of tumour, prevention of metastases.;2 cl, 1 ex
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机译：领域：本发明涉及药物，并且可以在眼科中用于突出超过4mm的中央和赤道前局部的脉络膜黑色素瘤（CM）的电化学裂解和光动力疗法。将光敏性PS引入巩膜的肿瘤区域并缝合后的2个小时是电极阳极，由铂丝制成网状，中心有孔，形状与肿瘤在巩膜上的突起形状相对应，大小为在整个周长上比肿瘤小1毫米;在光导体的肿瘤内部分的整个长度上制成的带有扩散器的激光光导体从铂的插入阴极到光导体的远端4.0mm的距离内玻璃体引入肿瘤。此后，进行肿瘤的电化学裂解，同时消融肿瘤破坏产物，然后通过激光导体对肿瘤进行基质内照射，该波长为对应于光照射的PS吸收最大值的波长的激光辐射。效果：本发明确保了通过电化学激光和脉络膜黑色素瘤的光动力疗法减少创伤，在肿瘤基底区域保留巩膜完整，完全破坏和消融肿瘤，防止转移。; 2 cl，1 ex
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