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METHOD FOR CONCENTRATING NATIBE O-ANTIGEN Vibrio cholerae

机译：浓缩纳豆O型抗原霍乱弧菌的方法

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FIELD: medicine, pharmaceutics.;SUBSTANCE: invention refers to a technology of medical immunobiological preparations, and concerns a method for concentrating a native O-antigen Vibrio cholerae. Substance of the invention involves concentrating the native O-antigen Vibrio cholerae with the use of a membrane with nominal molecular weight cut-off 500 kDa in cross-flow filtration at pressure 0.24-0.26 MPa, average specific filtration rate (79±2) dm³/m²/h.;EFFECT: ensured higher processing rate and decreased O-antigen loss by 40% with maintained quality parameters of the preparation.;3 ex, 3 tbl

机译：领域：本发明涉及医学免疫生物学制剂的技术，并且涉及浓缩天然O抗原霍乱弧菌的方法。本发明的内容涉及在0.24至0.26MPa的压力，平均比滤过率（79±2）dm的压力下的错流过滤中，使用截留分子量为500kDa的标称分子量截留膜，浓缩天然的O抗原霍乱弧菌。 ^{3 / m ^{2 / h .;效果：在保持制剂质量参数的前提下，确保了更高的加工速度并将O抗原损失降低了40％。3ex，3 tbl}}

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公开/公告号RU2445116C1

专利类型
公开/公告日2012-03-20

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE UCHREZHDENIE ZDRAVOOKHRANENIJA ROSSIJSKIJ NAUCHNO-ISSLEDOVATELSKIJ PROTIVOCHUMNYJ INSTITUT MIKROB FEDERALNOJ SLUZHBYPO NADZORU V SFERE ZASHCHITY PRAV POTREBITELEJ I BLAGOPOLUCHIJA CHELOVEKA (ROSNIPCHI MIKROB);
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申请/专利号RU20110108391
发明设计人 KOMISSAROV ALEKSANDR VLADIMIROVICH (RU);NIKIFOROV ALEKSEJ KONSTANTINOVICH (RU);EREMIN SERGEJ ALEKSANDROVICH (RU);ALESHINA JULIJA ALEKSANDROVNA (RU);GROMOVA OLGA VIKTOROVNA (RU);KRAJNOVA ANNA GENNADEVNA (RU);KLOKOVA OLGA DMITRIEVNA (RU);BELJAKOVA NINA IVANOVNA (RU);VASIN JURIJ GENNADEVICH (RU);
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申请日2011-03-03
分类号A61K39/106;A61P31/04;G01N33/569;
国家 RU
入库时间 2022-08-21 17:06:13

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