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METHOD OF SELECTION OF INDIVIDUAL DRUGS IN TREATMENT OF ARTERIAL HYPERTENSION

机译:高血压治疗中个体用药的选择方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, particularly clinical pharmacology and cardiology, and may be used for achieving target arterial pressure in the patients suffering degree 1-2 arterial hypertension (AH). A start antihypertensive preparation is individually selected by taking into account systolic arterial blood pressure (SABP) variations in passive orthostatic test. The measurements are taken in an initial horizontal position on the first, fifth, tenth and fifteenth minutes of the test. A response index (RI) is calculated by formula: If the RI is less than zero, a monotherapy with an angiotensin converting enzyme inhibitor is required. If the RI is equal to zero or more, a combined therapy with the angiotensin converting enzyme inhibitor Zofenopril and the beta-adrenoreceptor blocking agent Nebivolol is required.;EFFECT: method provides a differentiated approach to selection of the start therapy in this group of patients for achieving target pressure.;2 ex
机译:技术领域本发明涉及医学,尤其是临床药理学和心脏病学,并且可以用于在患有1-2级动脉高血压(AH)的患者中实现目标动脉压。通过在被动体位测试中考虑收缩期动脉血压(SABP)的变化,单独选择开始的降压制剂。在测试的第一,第五,第十和第十五分钟,在初始水平位置进行测量。响应指数(RI)由以下公式计算:如果RI小于零,则需要使用血管紧张素转化酶抑制剂的单药治疗。如果RI等于或大于零,则需要联合使用血管紧张素转化酶抑制剂佐芬普利和β-肾上腺素受体阻断剂奈比洛尔的联合疗法。效果:该方法为该组患者提供了差异化的开始疗法选择方法用于达到目标压力。; 2 ex

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