首页> 外国专利> STRAIN NADL-ARRIAW OF VIRUS OF VIRUS DIARRHEA OF CATTLE DIARRHEA VIRUS BOVINUM FOR PREPARING BIOLOGICAL BIOPREPARATIONS FOR DIAGNOSIS, AND SPECIFIC PROPHYLACTICS AND TREATMENT OF VIRUS DIARRHEA OF CATTLE

STRAIN NADL-ARRIAW OF VIRUS OF VIRUS DIARRHEA OF CATTLE DIARRHEA VIRUS BOVINUM FOR PREPARING BIOLOGICAL BIOPREPARATIONS FOR DIAGNOSIS, AND SPECIFIC PROPHYLACTICS AND TREATMENT OF VIRUS DIARRHEA OF CATTLE

机译：牛腹泻病毒牛腹泻病毒的应变纳德里亚尔用于诊断生物生物制剂的诊断，牛腹泻病毒的具体预防和治疗

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FIELD: chemistry.;SUBSTANCE: invention relates to veterinarian virology and biotechnology. A novel industrial strain NADL-ARRIAH of bovine viral diarrhoea is obtained. The strain is deposited in the microorganisms used in veterinary and animal husbandry of FGU VGNKI under registration number - industrial strain NADL-ARRIAH-DEP bovine viral diarrhoea. The strain is reproduced in passaged cultures of calf kidney cells, saiga finite cell line, intestinal mucus finite cell line, intraspecific swine embryo kidney hybrid finite cell line with swine splenocyte (A₄×C₂) at 37°C and in 72-96 hour of incubation, the virus accumulates therein in amount of 6.0-7.0 lg TCD₅₀/cm³. The strain is stable and retains its properties for 10 passages. The strain is used to obtain hyperimmune blood serum to bovine viral diarrhoea on rabbit and guinea pigs, used for agent diagnosis and treating animal diseases.The invention can be used in veterinary.;EFFECT: inactivated emulsion vaccine derived from said strain protects immunised animals from direct infection by a virulent virus.;1 dwg, 10 tbl, 7 ex

机译：技术领域本发明涉及兽医病毒学和生物技术。获得了牛病毒性腹泻的新型工业菌株NADL-ARRIAH。该菌株以注册号保藏在FGU VGNKI的兽医和畜牧业用微生物中-工业菌株NADL-ARRIAH-DEP牛病毒性腹泻。该菌株在小腿肾细胞，赛加羚羊有限细胞系，肠粘液有限细胞系，猪脾细胞与猪脾肾内种猪胚胎肾脏杂交有限细胞系（A _{4 ×C _{2 ）在37°C下孵育72-96小时后，病毒以6.0-7.0 lg TCD _{50 / cm ^{3 的量积累在其中。该菌株是稳定的，并保留其特性10次。该菌株用于获得兔和豚鼠的牛病毒性腹泻的超免疫血清，用于试剂诊断和治疗动物疾病。本发明可用于兽医。效果：该菌株衍生的灭活乳剂疫苗可保护免疫的动物免于感染。直接被强力病毒感染。; 1 dwg，10 tbl，7 ex}}}}

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公开/公告号RU2010127726A

专利类型
公开/公告日2012-01-10

原文格式PDF
申请/专利权人 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ УЧРЕЖДЕНИЕ ФЕДЕРАЛЬНЫЙ ЦЕНТР ОХРАНЫ ЗДОРОВЬЯ ЖИВОТНЫХ (ФГУ ВНИИЗЖ) (RU);
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申请/专利号RU20100127726
发明设计人 МИЩЕНКО ВЛАДИМИР АЛЕКСАНДРОВИЧ (RU);КОРПУСОВА ТАТЬЯНА ИВАНОВНА (RU);КОНОНОВ АЛЕКСАНДР ВЛАДИМИРОВИЧ (RU);ПРОХВАТИЛОВА ЛАРИСА БОРИСОВНА (RU);ЛЕВЧЕНКО СВЕТЛАНА ВЛАДИМИРОВНА (RU);
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申请日2010-07-05
分类号C12N7/00;
国家 RU
入库时间 2022-08-21 17:06:52

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