首页> 外国专利> A NEW THERAPEUTIC DRUG FOR THE TREATMENT OF ALLERGIC ASTHMA CONTAINING PYRANOPYRAN-1,8-DIONE

A NEW THERAPEUTIC DRUG FOR THE TREATMENT OF ALLERGIC ASTHMA CONTAINING PYRANOPYRAN-1,8-DIONE

机译：一种新的治疗药物，用于治疗含吡喃并吡喃-1,8-二酮的过敏性哮喘

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摘要

The present invention Vitexrotundifolia Linne is a compound extracted from the fruit of pyrano-pyran-1,8-fil (Verbenaceae) relates to the use of an ion as asthma. The compounds inhibit the migration of eosinophils by suppressing signaling pathways involved. Therefore, it is effective as a novel therapeutic agent for asthma, including allergic disorders associated with secretion and / or the movement of the eosinophil eotaxin. ; Asthma, eosinophil, eotaxin, pyrano-pyran-1,8-dione (1H, 8H-Pyrano [3,4-c] pyran-1,8-dione), OVA, A549 cells, BALF

机译：本发明的 Vitex 圆叶花亚麻是从吡喃-吡喃-1，8-fil（马鞭草科）的果实中提取的化合物，涉及离子作为哮喘的用途。该化合物通过抑制所涉及的信号传导途径来抑制嗜酸性粒细胞的迁移。因此，它作为哮喘的新型治疗剂是有效的，包括与嗜酸性粒细胞嗜酸性粒细胞趋化因子的分泌和/或运动有关的过敏性疾病。 ;哮喘，嗜酸性粒细胞，嗜酸性粒细胞趋化因子，吡喃吡喃-1,8-二酮（1H，8H-吡喃[3,4-c]吡喃-1,8-二酮），OVA，A549细胞，BALF 展开▼

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公开/公告号KR101119719B1

专利类型

公开/公告日2012-03-09

原文格式PDF

申请/专利权人
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申请/专利号KR20090052858

发明设计人 이희경;한아름;배현수;
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申请日2009-06-15

分类号A61K31/35;A61P11/06;A61P37/08;A61P17/00;

国家 KR

入库时间 2022-08-21 17:08:30

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1. 用于治疗HIV以及其他逆转录病毒的吡喃-2-酮及5，6-二氢吡喃-2-酮 [P] . 中国专利： CN1090279A . 1994-08-03

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3. THERAPEUTIC AGENT FOR ASTHMA CONTAINING PYRANOPYRAN-1,8-DIONE [P] . 韩国专利： KR20100134305A . 2010-12-23

机译：含吡喃吡喃-1,8-二酮的哮喘治疗剂

4. "compound, use of this or a pharmacologically acceptable salt, ester or other derivative thereof, medication, preventive or therapeutic agents for asthma and / or bronchitis, for rhinitis, for allergic disease, and for urinary incontinence, and, prevention processes or treatment of asthma and / or bronchitis, rhinitis, allergic disease, and urinary incontinence. " [P] . BR9815348A . 2000-10-17

机译： “该化合物或其药理学上可接受的盐，酯或其他衍生物的用途，用于哮喘和/或支气管炎，鼻炎，过敏性疾病和尿失禁的药物，预防或治疗剂，以及预防或治疗哮喘和/或支气管炎，鼻炎，过敏性疾病和尿失禁。”

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机译：除虫菊酯或其盐的7-（杂环，芳基或异晶）衍生物;包括这些化合物的药物合成，用于治疗PTK Quinasa诱发的疾病，例如过敏性哮喘，过敏性肾炎，类风湿性关节炎，多发性硬化症，狼疮性白血病和其他疾病

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