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BPB-BASED CARGO DELIVERY SYSTEM FOR IN VIVO MOLECULE IMAGING, IN VITRO CELL IMAGING, AND TARGETING FOR DRUG DELIVERY
BPB-BASED CARGO DELIVERY SYSTEM FOR IN VIVO MOLECULE IMAGING, IN VITRO CELL IMAGING, AND TARGETING FOR DRUG DELIVERY
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机译:基于BPB的货物递送系统,用于体内分子成像,体外细胞成像和靶向药物递送
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摘要
PURPOSE: A BPB-based cargo delivery system is provided to enable delivering various substances to the surface of cells or the inside of the cells and to ensure high affinity to a target.;CONSTITUTION: A BPB-based cargo delivery system contains: a bipodal peptide binder(BPB) and a cargo conjugated to the bipodal peptide binder. The bipodal peptide binder contains a parallel, antiparallel, or structure stabilizing region; and a target binding regions I and II containing n and m numbers of amino acids which are randomly selected. The non-covalent bond is formed at the structure stabilizing region by hydrogen bond, electrostatic interaction, hydrophobic interaction, van der Waals interaction, pi-pi interaction, cation-pi interaction, or combination thereof.;COPYRIGHT KIPO 2013
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