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AGT GENE POLYMORPHISMS MARKER FOR DIAGNOSING ASPIRIN INTOLERANT ASTHMA WITH MODIFIED RESPONSE TO MONTELUKAST TREATMENT
AGT GENE POLYMORPHISMS MARKER FOR DIAGNOSING ASPIRIN INTOLERANT ASTHMA WITH MODIFIED RESPONSE TO MONTELUKAST TREATMENT
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机译:AGT基因多态性标记物,用于诊断阿司匹林耐受不良的哮喘,对孟鲁司特治疗的反应有所改善
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摘要
PURPOSE: An AGT gene polymorphism marker for diagnosing AIA(aspirin intolerant asthma) is provided to prevent and treat asthma as a pharmacological marker. CONSTITUTION: An AGT(anginotensinogen) gene polymorphism marker for diagnosing AIA(aspirin intolerant asthma) responses to a therapeutic agent for asthma. The marker contains SNP from a polynucleotide with a DNA sequence of sequence number 1. A SNP has 546th base(T or C), 6991th(C or G), and 7066th(C or T). A method for detecting AGT gene polymorphism marker comprises: a step of isolating genome DNA from a test sample; and a step of detecting polynucleotide in the genome DNA.
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