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EARLY DIAGNOSIS OF CHILDHOOD WHEEZE AND ECZEMA WITH MEDIATORS FROM CORD BLOOD MONONUCLEAR
EARLY DIAGNOSIS OF CHILDHOOD WHEEZE AND ECZEMA WITH MEDIATORS FROM CORD BLOOD MONONUCLEAR
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机译：脐血单核介导的儿童口气和幼虫的早期诊断
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摘要
The invention relates to methods of diagnosing risk of an individual to suffer from an inflammatory disorder, method of identifying a compound which can modulate the inflammatory response caused by an inflammatory disorder in an individual, and protein array kits for carrying out the methods. The methods comprising measuring in a sample from an individual a level of Interleukin 10 (IL-10) and a level of at least two substances selected from the group consisting of cluster of differentiation 14 (CD14) and tumor necrosis factor receptor type II (TNF-RII) or isoforms or fragments of TNF-RII and CD14; tissue inhibitor of matrix metalloproteinase-1 (TIMPl) and TNF-RII or isoforms or fragments of TIMPl and TNF-RII; and CD 14, TIMPl and TNF-RII or isoforms or fragments of CD 14, TIMPl and TNF-RII; and comparing the measured level with a level measured in a control.
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机译：本发明涉及诊断个体患有炎性疾病的风险的方法，鉴定可调节个体中由炎性疾病引起的炎性反应的化合物的方法以及用于实施该方法的蛋白质阵列试剂盒。该方法包括在个体样品中测量白细胞介素10（IL-10）的水平和至少两种选自分化簇14（CD14）和II型肿瘤坏死因子受体（TNF）的物质的水平。 -RII）或TNF-RII和CD14的同工型或片段;基质金属蛋白酶-1（TIMP1）和TNF-RII或TIMP1和TNF-RII的同工型或片段的组织抑制剂; CD 14，TIMP1和TNF-RII或CD 14，TIMP1和TNF-RII的同工型或片段;并将所测量的水平与对照中所测量的水平进行比较。
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