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GENE EXPRESSION PROFILING FOR PREDICTING THE RESPONSE TO IMMUNOTHERAPY AND/OR THE SURVIVABILITY OF MELANOMA SUBJECTS

机译:基因表达谱用于预测对黑色素瘤患者的免疫治疗和/或可生存性

摘要

A method is provided in various embodiments for determining a profile data set for predicting the response top immunotherapy and or survivability of a subject with melanoma based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification under measurement conditions that are substantially repeatable for measuring the amount of RNA corresponding to at least 2, 3 or 4 constituents according to the gene models shown in Tables 2-3, 4-6 and 9.
机译:在各种实施方式中提供了一种方法,该方法用于基于来自受试者的样品来确定用于预测受试者的应答性最高免疫疗法和/或黑色素瘤的存活率的概况数据集,其中所述样品提供RNA的来源。该方法包括在基本上可重复的测量条件下使用扩增,以根据表2-3、4-6和9中所示的基因模型测量对应于至少2、3或4个成分的RNA量。

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