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PECTIN COMPLEXES OF SARTANS AND PHARMACEUTICAL COMPOSITIONS BASED THEREON

机译:斯大林果胶复合物和基于其的药物组合物

摘要

The present solution relates to a method of manufacturing a pharmaceutical composition containing an active substance of the sartan type in the form of an adduct (complex) with a pectin, optionally in a mixture with a glucan. The resulting adduct is characterized by higher solubility in water as compared with the original pharmaceutically active substance. The adduct (complex) consisting of the active substance and pectin is then used for preparing a dosage form with targeted (controlled) release in the intestine.
机译:本解决方案涉及一种制造药物组合物的方法,该药物组合物包含与果胶加合物(复合物)形式的,任选地与葡聚糖混合的形式的沙坦型活性物质。与原始的药物活性物质相比,所得加合物的特征在于在水中的溶解度更高。然后将由活性物质和果胶组成的加合物(复合物)用于制备在肠道内靶向(控制)释放的剂型。

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