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Halogenated aliphatic carboxylic acids, oligomers and/or polymers thereof and their use in devitalizing external and internal neoplasms

机译:卤代脂肪族羧酸,低聚物和/或其聚合物及其在使外部和内部肿瘤丧失活力方面的用途

摘要

Halogenated aliphatic carboxylic acids, salts and/or oligomers or polymers thereof, which exhibit a devitalizing effect of neoplastic tissues, are disclosed. Methods and uses that utilize these compounds for the treatment of medical conditions associated with a neoplastic tissue are also disclosed. Further disclosed are methods and uses that utilize these compounds for reducing or abolishing blood and lymph as well local dissemination of malignant neoplastic cells during a surgical removal thereof, thereby preventing recurrences and distance metastases, and/or inducing immune response to potentially malignant, pre-malignant and/or malignant cells. Further disclosed are novel oligomeric forms of halogenated aliphatic carboxylic acids, pharmaceutical compositions containing same and uses thereof.
机译:公开了表现出赘生性组织的灭活作用的卤代脂族羧酸,盐和/或低聚物或聚合物。还公开了利用这些化合物治疗与赘生性组织有关的医学病症的方法和用途。进一步公开了利用这些化合物在手术切除期间减少或消除血液和淋巴液以及恶性肿瘤细胞的局部扩散的方法和用途,从而防止复发和距离转移,和/或诱导对潜在恶性,前期恶性肿瘤的免疫应答。恶性和/或恶性细胞。进一步公开了卤代脂族羧酸的新型低聚形式,包含其的药物组合物及其用途。

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