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Method of reducing the risk of adverse cardiovascular (CV) events associated with the administration of pharmaceutical agents which favor CV events
Method of reducing the risk of adverse cardiovascular (CV) events associated with the administration of pharmaceutical agents which favor CV events
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机译:减少与有利于心血管事件的药剂的给药相关的不良心血管事件发生风险的方法
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摘要
Methods and compositions for reducing the risks of adverse cardiovascular (CV)events associated with the administration of pharmaceutical agents which induceor increase the risk of one or more adverse CV events, particularly the non-steroidalanti-inflammatory drags (NSAIDs) and especially the cyclooxygenase-2 (COX-2)inhibitors, are disclosed. The methods involve the administration of compositionscomprising the adverse CV event-inducing agent and additional pharmaceuticalagents for reducing the risk of adverse CV events. In specific embodiments, theagent is selected from the group consisting of hydroxymethylglutaryl-coenzymeA reductase inhibitors (statins), angiotensin converting enzyme (ACE) inhibitorsand angiotensin II receptor blockers (ARBs).
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