首页> 外国专利> Use of Panton-Valentine Leukocidin for treating and preventing Staphylococcus infections

Use of Panton-Valentine Leukocidin for treating and preventing Staphylococcus infections

机译:Panton-Valentine Leukocidin在治疗和预防葡萄球菌感染中的用途

摘要

The present invention relates to compositions and methods for treating infections. In particular, the present invention providesvaccines comprising a Panton- Valentine Leukocidin (PVL) antigen, antibodieswhich bind a PVL antigen and compositions containing the same, methods of makingsuch compositions and methods for treating infections, includingthose that are community acquired methicillin-resistant infections. The presentinvention also provides PVL antibodies, including PVL antibodies specificfor a single PVL subunit, and PVL antigens, including conjugated and mutatedPVL antigens.
机译:本发明涉及治疗感染的组合物和方法。特别地,本发明提供包含Panton- Valentine Leukocidin(PVL)抗原的疫苗,抗体结合PVL抗原的抗原及其组合物,制备方法此类组合物和治疗感染的方法,包括社区感染者获得耐甲氧西林的感染。现在本发明还提供了PVL抗体,包括特异性的PVL抗体用于单个PVL亚基和PVL抗原,包括缀合和突变PVL抗原。

著录项

  • 公开/公告号AU2006257774B2

    专利类型

  • 公开/公告日2012-03-01

    原文格式PDF

  • 申请/专利权人 GLAXOSMITHKLINE BIOLOGICALS SA;

    申请/专利号AU20060257774

  • 发明设计人 FATTOM ALI IBRAHIM;TAYLOR KIMBERLY LOUISE;

    申请日2006-06-13

  • 分类号C07K16/12;A61K39/085;A61K39/395;A61P31/04;C07K14/31;

  • 国家 AU

  • 入库时间 2022-08-21 17:19:59

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