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METHODS AND PRODUCTS FOR IN VITRO GENOTIPATE OF HUMAN GENETIC VARIATIONS ASSOCIATED WITH REACTIONS ADVERSE TO DRUGS.
METHODS AND PRODUCTS FOR IN VITRO GENOTIPATE OF HUMAN GENETIC VARIATIONS ASSOCIATED WITH REACTIONS ADVERSE TO DRUGS.
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机译:与药物不良反应相关的人类遗传变异的体外基因组方法和产品。
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摘要
Methods and products for in vitro genotyping of human gene variations associated with adverse drug reactions. # The genotyping method is based on the combination of an experimental design of genotyping DNA-chips and on the development of a sequential processing and interpretation system. of the experimental data generated by said genotyping DNA-chips based on the increase in the hybridization signal, which guarantees high levels of specificity, sensitivity and reproducibility of the results, which allow said DNA-chips to be used as tools reliable clinical genetic diagnosis; in particular, in the detection of gene variations, for example, polymorphisms or gene mutations associated with resistance to pharmacological treatments.
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