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TOLL LIKE RECEPTOR 4-DYSFUNKTION AND BIOLOGICAL APPLICATIONS THEREOF
TOLL LIKE RECEPTOR 4-DYSFUNKTION AND BIOLOGICAL APPLICATIONS THEREOF
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机译:类似于受体的受体4-失功能及其生物学应用
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摘要
The present invention relates to an in vitro method of assessing the sensitivity of a subject to a treatment of cancer, which method comprises detecting the presence of a mutated Toll Like Receptor 4 (TLR4) nucleic acid or an abnormal TLR4 protein expression or activity in a sample from the subject, the presence of said mutated TLR4 nucleic acid or abnormal TLR4 expression or activity being indicative of a resistance to said treatment. The detection of the presence of a mutated Toll Like Receptor 4 (TLR4) nucleic acid or an abnormal TLR4 protein expression or activity in a sample from a subject is also indicative of a predisposition to a cancer in the subject.
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