首页> 外国专利> MECHANICAL PROTECTIVE LAYER FOR SOLID DOSAGE FORMS COMPRISING TWO POLYETHYLENE GLYCOLS OF DIFFERING MOLECULAR WEIGHT

MECHANICAL PROTECTIVE LAYER FOR SOLID DOSAGE FORMS COMPRISING TWO POLYETHYLENE GLYCOLS OF DIFFERING MOLECULAR WEIGHT

机译:包含两种分子量不同的聚乙烯二醇的固体剂型的机械保护层

摘要

Disclosed is a mechanical protective layer for a dosage form comprising two or more plasticizer agents, where in a first plasticiser agent is a first polyethylene glycol (PEG) with an average molecular weight lower than 6,000 and a second plasticizer agent is a second polyethylene glycol different from the first polyethylene glycol, and wherein said mechanical protective layer is disposed on an enteric coated pellet. Further disclosed is the use of a mechanical protective layer which comprises two or more plasticizer agents, where in a first plasticiser agent is a first polyethylene glycol (PEG) with an average molecular weight lower than 6,000 and a second plasticizer agent is a second polyethylene glycol different from the first polyethylene glycol for the manufacture of solid dosage forms.
机译:公开了包含两种或更多种增塑剂的剂型的机械保护层,其中在第一增塑剂中是平均分子量低于6,000的第一聚乙二醇(PEG),而第二增塑剂是不同的第二聚乙二醇由第一聚乙二醇制备,其中所述机械保护层位于肠溶包衣的小丸上。进一步公开了包含两种或更多种增塑剂的机械保护层的用途,其中在第一增塑剂中是平均分子量低于6,000的第一聚乙二醇(PEG),第二增塑剂是第二聚乙二醇。与第一种用于制备固体剂型的聚乙二醇不同。

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