首页>
外国专利>
A PHARMACUTICAL COMPOSITION CONTAINING RISEDRONATE
A PHARMACUTICAL COMPOSITION CONTAINING RISEDRONATE
展开▼
机译：包含利思膦酸盐的药物组合物
展开▼
页面导航
摘要
著录项
相似文献
摘要
A pharmaceutical composition comprising risedronate, a chelating agent, and, means for effecting delayed release of the risedronate and the chelating agent in the small intestine provide immediate release of the pharmaceutical composition to the small intestine of the mammal subject and pharmaceutically effective absorption of the bisphosphonate with or without food or beverages. The present invention substantially alleviates the interaction between risedronate and food or beverages, which interaction results in the bisphosphonate active ingredient not being available for absorption. The resulting pharmaceutical composition may thus be taken with or without food. Further, the present invention effects delivery of risedronate and the chelating agent to the small intestine, substantially alleviating the upper GI irritation associated with bisphosphonate therapies. These benefits simplify previously complex treatment regimens and can lead to increased patient compliance with bisphosphonate therapies.
展开▼
