首页> 外国专利> A separated von Willebrand factor polypeptide (FVW) includes a binding factor VIII domain in which the polypeptide lacks certain VW domains, including an immunoglobulin monocarbamate sequence, composition and protein complexes, including cells; It expresses polyacrylic acid; cells that express this protein complex; including the components of the protein complex.

A separated von Willebrand factor polypeptide (FVW) includes a binding factor VIII domain in which the polypeptide lacks certain VW domains, including an immunoglobulin monocarbamate sequence, composition and protein complexes, including cells; It expresses polyacrylic acid; cells that express this protein complex; including the components of the protein complex.

机译：分离的von Willebrand因子因子多肽（FVW）包括结合因子VIII结构域，其中该多肽缺乏某些VW结构域，包括免疫球蛋白单氨基甲酸酯序列，组成和蛋白质复合物，包括细胞;它表示聚丙烯酸;表达这种蛋白质复合物的细胞;包括蛋白质复合物的成分。

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pPolipeacute; peptide comprising a first amino acid sequence present in a polypeacute; von Willebrand factor peptide (FVW) and a second aminoaacute sequence; heteroacute; loga with respect to the first, wherein said polypeptide; peptide it is capable of joining an FVIII, with the proviso that said polypeptide does not have some FVW domains; nucleotiacute sequences, vectors, cells that encode it; meacute; all for its production; composition; and its therapeutic use to treat a blood disorder./p

机译：polipeacute;包含存在于多聚纤维素中的第一氨基酸序列的肽; von Willebrand因子肽（FVW）和第二个氨基急性序列;异质性关于第一个loga，其中所述多肽;能够结合FVIII的肽，条件是所述多肽不具有某些FVW结构域;核苷酸序列，载体，编码它的细胞; ac全部用于生产;组成;及其治疗血液疾病的用途。

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公开/公告号CL2012001258A1

专利类型
公开/公告日2012-09-14

原文格式PDF
申请/专利权人 GRIFOLS THERAPEUTICS INC.;
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申请/专利号CL20120001258
发明设计人 BARNETT THOMAS;
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申请日2012-05-14
分类号A61K38/17;A61P7/00;C07K19/00;C12N15/62;C12N15/63;
国家 CL
入库时间 2022-08-21 17:25:19

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