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Use of the ratio of ventricular enlargement for the treatment of Alzheimer's disease with intravenous immunoglobulin and Method for evaluating the therapeutic efficacy
Use of the ratio of ventricular enlargement for the treatment of Alzheimer's disease with intravenous immunoglobulin and Method for evaluating the therapeutic efficacy
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机译：心室扩大比在静脉注射免疫球蛋白治疗阿尔茨海默氏病中的用途和评估疗效的方法
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摘要
Requirement 1: methods of treatment in patients with Alzheimer's disease, including (a) sequential steps to determine the volume of the patient's central ventricle through magnetic resonance imaging (IRM),Therefore, a reference value of ventricular volume was obtained; (b) a therapeutic agent to keep the brain was used for the treatment of Alzheimer's disease for the first time; (c) the ventricular volume of the brain was determined by IRM. Therefore, the first intermediate value of ventricular volume was obtained; (d) the intermediate value of stage (c) was compared with the reference value of stage (a);(e) When level (d) indicates an increase from the reference value to the first intermediate value, and the increase is equal to or greater than the expected increase in ventricular volume of Alzheimer's patients, but without treatment, the use of brain preservation therapy agent with increased dose or frequency is increased Treatment of the disease within the same period as the first period,Or maintain the use of brain maintaining dose or frequency therapeutics when (d) indicates that there is no increase from the reference value to the first intermediate value, or that the increase is less than the increaseIt is expected to be within the ventricular volume of patients with Alzheimer's, but not treated for the same period of time as the first cycle.There, the therapeutic agent is a therapeutic agent that protects the brain through immunoglobulins. Claim 7: method of claim 1, wherein the therapeutic agent is immunoglobulin injection (lglv).
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