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DNA CHIP, KIT FOR DETECTING OR GENOTYPING BACTERIA CAUSING SEXUALLY TRANSMITTED DISEASES, GENOTYPING ANTIBACTERIAL DRUG RESISTANCE AND DETECTING OR GENOTYPING METHOD USING THE SAME
DNA CHIP, KIT FOR DETECTING OR GENOTYPING BACTERIA CAUSING SEXUALLY TRANSMITTED DISEASES, GENOTYPING ANTIBACTERIAL DRUG RESISTANCE AND DETECTING OR GENOTYPING METHOD USING THE SAME
Disclosed are a DNA chip and a kit capable of quickly and accurately detecting or genotyping the highly prevalent and important eleven microbes causing sexually transmitted diseases (STD) Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma genitalium, Mycoplasma hominis, syphilis-causing treponema, pallidum, chancroid-causing Haemophilus ducreyi, genital herpes-causing herpes simplex virus 1 and 2, human papillomavirus (HPV) and Trichomonas vaginalis and three related organisms Candida albicans, Gardnerella vaginalis and coliform bacteria and analyzing antibiotic resistance against tetracycline and lactam antibiotics, and a method for detecting or genotyping using the same. According to the present invention, the presence, genotype and antibiotic resistance of the fourteen organisms can be analyzed quickly and accurately from a DNA sample. With excellent sensitivity, specificity, reproducibility and accuracy of the 14 STD-causing and related microorganisms may be automatically identified quickly and accurately from multiple samples, and selection of antibiotics may be aided.
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机译:公开了一种DNA芯片和试剂盒,其能够快速,准确地检测或分析引起性传播疾病(STD)的高度流行和重要的11种微生物淋病奈瑟氏球菌,沙眼衣原体,解脲脲原体,生殖器支原体,人支原体 I >,引起梅毒的梅毒,苍白球 I>,导致类c液的嗜血杆菌Ducreyi I>,引起生殖器疱疹的单纯疱疹病毒1、2,人乳头瘤病毒(HPV)和滴虫阴道炎和三种相关生物白念珠菌,阴道加德纳菌和大肠菌,并分析其对四环素和内酰胺类抗生素的耐药性,以及使用它们进行检测或基因分型的方法。根据本发明,可以从DNA样品中快速和准确地分析十四种生物的存在,基因型和抗生素抗性。可以从多个样品中快速,准确地自动识别出14种引起STD的微生物和相关微生物的灵敏度,特异性,可重复性和准确性,并可以帮助选择抗生素。
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