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METHOD AND COMPOSITION FOR TARGETING VICIOUS CYCLES OF STRESSES AND INFLAMMATORY RESPONSES
METHOD AND COMPOSITION FOR TARGETING VICIOUS CYCLES OF STRESSES AND INFLAMMATORY RESPONSES
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机译:定位应力和炎症反应的生命周期的方法和组成
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摘要
The present invention provides methods and compositions for targeting the pathologically relevant bipolar actions of these master integrators without affecting the basal physiologically relevant functions. NFA can be used as marker of vicious cycles. Partial inhibition of NFA will be less toxic (in most cases) and more efficient for simultaneous partial inhibitions of all key mediators to terminate this vicious cycles for prevention and treatment of the long-term stresses and chronic inflammation-related diseases without causing any side effects and complications. Aberrant expression of NFA, master stress, and inflammation integrators play a role in orchestrating of vicious cycles. Aspects of the invention provide core technology for simultaneously targeting 12 hallmarks of cancer.
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