METHOD OF A RHEIN COMPOUND FOR INHIBITING PANCREATIC ISLET BETA-CELL DYSFUNCTION AND PREVENTING OR TREATING A PANCREATIC ISLET BETA-CELL DYSFUNCTION RELATED DISORDER

• 1. 大黄酸类化合物或其盐在制备预防和治疗胰岛β细胞功能衰退药物中的应用 [P] . 中国专利： CN101822660B . 2013.07.10
• 2. 大黄酸类化合物或其盐在制备预防和治疗胰岛β细胞功能衰退药物中的应用 [P] . 中国专利： CN101822660A . 2010-09-08
• 3. METHODS AND COMPOSITIONS RELATING TO PANCREATIC ISLET AND BETA-CELL DYSFUNCTION [P] . 欧洲知识产权局专利： EP1194777B1 . 2006-11-22

  机译： 与胰岛和β-细胞功能障碍有关的方法和成分

• 4. Methods and compositions relating to pancreatic islet and beta-cell dysfunction [P] . AU781477B2 . 2005-05-26

  机译： 与胰岛和β细胞功能障碍有关的方法和成分

• 5. Methods and compositions relating to pancreatic islet and beta-cell dysfunction [P] . AU781477C . 2005-11-10

  机译： 与胰岛和β细胞功能障碍有关的方法和成分

• 1. Relationship between Free Thyroxine and Islet Beta-cell Function in Euthyroid Subjects [J] . Qing LI, Meng LU, Ning-jian WANG, 当代医学科学(英文) . 2020,第001期
• 2. Linoleic Acid Activates GPR40/FFA1 and Phospholipase C to Increase Ca2+i Release and Insulin Secretion in Islet Beta-Cells [J] . Yi-jun Zhou, Yu-ling Song, Hui Zhou, 中国医学科学杂志（英文版） . 2012,第001期
• 3. Protein disulfide isomerase ameliorates beta-cell dysfunction in pancreatic islets overexpressing human islet amyloid polypeptide [J] . Montane Joel, de Pablo Sara, Obach Merce, Molecular and Cellular Endocrinology . 2016,第3期
• 4. A role of pancreatic stellate cells in islet fibrosis and beta-cell dysfunction in type 2 diabetes mellitus [J] . Biochemical and Biophysical Research Communications . 2017,第2期
• 5. Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet beta-cells: reversal of such metabolic defects by metformin [J] . Baidwan Sartaj, Chekuri Anil, Hynds DiAnna L., Apoptosis: An international journal on programmed cell death . 2017,第11期
• 6. Enhanced beta-cell pancreatic islet formation using laminin-functionalised dendrons tethered to poly-L-lysine [C] . Mark Best, Valeria Perugini, Gary J Phillips, World biomaterials congress . 2016
• 7. Estrogen Receptor Activation Suppresses Lipogenesis and Reduces Lipid Accumulation in Pancreatic Islets and Prevents Lipotoxic beta-cell Failure [D] . Tiano, Joseph P. 2012
• 8. Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation. [O] . Emma T A S Jaikaran, Melanie R Nilsson, Anne Clark 2004
• 9. Oxidative stress induces p21 expression in pancreatic islet cells: possible implication in beta-cell dysfunction [O] . H. Kaneto, Y. Kajimoto, Y. Fujitani, 1999

• 1. Differentiation of rat marrow mesenchymal stem cells into pancreatic islet beta-cells [J] . Li-BoChen Xiao-BingJiang LianYang . 世界胃肠病学杂志：英文版 . 2004,第20期
• 2. Resveratrol Attenuates Benzo(a)pyrene-Induced Dysfunctions,Oxidative Stress and Apoptosis in Pancreatic Beta-Cells [J] . Sefa Celik ,Baris Baysal ,Serkan Sen . 生命科学与技术进展（英文） . 2019,第11期
• 3. Fentanyl inhibits glucose-stimulated insulin release from β-cells in rat pancreatic islets [J] . Tao-Lai Qian ,Xin-Hua Wang ,Sheng Liu . 世界胃肠病学杂志：英文版 . 2009,第33期
• 4. 杨梅黄酮通过Wnt通路改善细胞因子诱导的胰岛β细胞功能障碍的实验研究 [C] . 丁叶 ,戴小倩 ,张召锋 . 2012环境健康与药物安全性全国学术年会 . 2012
• 5. 表没食子儿茶毒没食子酸酯(EGCG)改善脂毒性诱导的大鼠外周胰岛素抵抗及胰岛β细胞功能障碍的实验研究 [A] . 李艳 . 2011