embedded image ;with the substituents being described herein."/> BENZOFURO3,2-c PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA
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首页> 外国专利> BENZOFURO3,2-c PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA

BENZOFURO3,2-c PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA

机译：苯并呋喃[3,2-c]吡啶类及相关类似物作为5-羟色胺亚型6（5-HT6）调节剂，用于治疗肥胖，代谢综合征，认知障碍和精神分裂症

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摘要

The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT6) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I); embedded image ;with the substituents being described herein.
机译：本发明涉及作为5-羟色胺亚型6（5-HT 6 ）调节剂的苯并呋喃[3,2-c]吡啶和氮杂pine类似物，包括这些化合物的药物组合物，制备方法和用途其。这些化合物可用于治疗中枢神经系统疾病，包括肥胖，代谢综合症，认知，精神分裂症，注意力缺陷多动障碍，躁郁症，罕见和孤儿疾病以及睡眠障碍。标题化合物具有式（I）的结构; “嵌入式图像” ;其中取代基在本文中描述。

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