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METHODS AND SYSTEM FOR VALIDATING SAMPLE IMAGES FOR QUANTITATIVE IMMUNOASSAYS

机译:用于验证定量免疫分析的样本图像的方法和系统

摘要

A method and system for automatically evaluating quality of a slide-mounted tissue sample includes receiving a digital image of a magnified portion of the slide-mounted tissue sample. At least one quantitative quality indicator is automatically determined for at least one of the samples, and the digital image of the magnified portion of the sample. Each of the quantitative quality indicators is automatically compared to a respective minimum acceptable quality threshold. The quantitative quality indicators and associated quality thresholds are selected for suitability with an automated quantitative immunoassay. Failure of one or more of the quantitative quality indicators to meet its respective minimum acceptable quality threshold suggests that the sample is unsuitable for subsequent automated pathological evaluation. Results can be examined at a user interface allowing for user inspection of samples determined to be unsuitable, the user interface also having provisions for manual override of the determination.
机译:一种用于自动评估载玻片组织样品的质量的方法和系统,包括接收载玻片组织样品的放大部分的数字图像。自动为至少一个样本以及样本的放大部分的数字图像确定至少一个定量质量指标。自动将每个定量质量指标与相应的最小可接受质量阈值进行比较。选择定量质量指标和相关的质量阈值以适合于自动化定量免疫测定。一个或多个定量质量指标未能达到其各自的最低可接受质量阈值,表明该样品不适合进行后续的自动病理学评估。可以在用户界面上检查结果,从而允许用户检查确定为不合适的样品,该用户界面还具有手动覆盖确定的规定。

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