首页> 外国专利> Hepatitis C virus cell culture system, hepatitis C virus-RNA-construct, use of cell culture system or construct, method for obtaining mutants compatible with hepatitis C virus-RNA-construct cell culture, hepatitis C Method for making a virus-full-length genome, hepatitis C virus-partial genome, or any hepatitis C virus-construct mutant, hepatitis C virus-construct adapted for cell culture, mutant thereof, hepatitis C virus -Full-length genome mutants, hepatitis C virus particles or virus-like particles, and cells infected therewith

Hepatitis C virus cell culture system, hepatitis C virus-RNA-construct, use of cell culture system or construct, method for obtaining mutants compatible with hepatitis C virus-RNA-construct cell culture, hepatitis C Method for making a virus-full-length genome, hepatitis C virus-partial genome, or any hepatitis C virus-construct mutant, hepatitis C virus-construct adapted for cell culture, mutant thereof, hepatitis C virus -Full-length genome mutants, hepatitis C virus particles or virus-like particles, and cells infected therewith

机译:丙型肝炎病毒细胞培养系统,丙型肝炎病毒RNA构建体,细胞培养系统或构建体的用途,获得与丙型肝炎病毒RNA构建体相容的突变体的方法,丙型肝炎全长病毒的制备方法基因组,丙型肝炎病毒部分基因组或任何丙型肝炎病毒构建体突变体,适用于细胞培养的丙型肝炎病毒构建体,其突变体,丙型肝炎病毒全长基因组突变体,丙型肝炎病毒颗粒或类病毒颗粒,以及被其感染的细胞

摘要

Hepatitis C virus (HCV) cell culture system comprising human hepatoma cells that contain an integrated HCV-RNA construct (I) new. (I) contains the HCV-specific RNA segments 5'-NTR (non-translated region), NS (non-structural)3, NS4A, NS4B, NS5A, NS5B and 3'-NTR, and a selectable (marker) gene (II). An Independent claim is also included for (I) containing the novel HCV-specific RNA segments.
机译:丙型肝炎病毒(HCV)细胞培养系统,其中包含含有新整合的HCV-RNA构建体(I)的人肝癌细胞。 (I)包含HCV特异性RNA片段5'-NTR(非翻译区),NS(非结构)3,NS4A,NS4B,NS5A,NS5B和3'-NTR,以及一个可选择的(标记)基因( II)。 (I)也包含独立的权利要求,其中包含新的HCV特异性RNA片段。

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